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Population pharmacokinetic analysis of cilostazol in healthy subjects with genetic polymorphisms of CYP3A5, CYP2C19 and ABCB1

AIMS: To investigate the influence of genetic polymorphisms in the CYP3A5, CYP2C19 and ABCB1 genes on the population pharmacokinetics of cilostazol in healthy subjects. METHODS: Subjects who participated in four separate cilostazol bioequivalence studies with the same protocols were included in this...

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Détails bibliographiques
Auteurs principaux: Yoo, Hee-Doo, Cho, Hea-Young, Lee, Yong-Bok
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830595/
https://ncbi.nlm.nih.gov/pubmed/20078610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03558.x
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