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Polymer-Cisplatin Conjugate Nanoparticles for Acid-Responsive Drug Delivery

We report the synthesis of novel acid-responsive therapeutic nanoparticles (NPs) with sub-100 nm size consisting of polymer-cisplatin conjugates. The uniqueness of these drug delivery polymeric NPs lies in the covalent conjugation of each cisplatin drug to the hydrophobic segment of two biocompatibl...

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Detalhes bibliográficos
Main Authors: Aryal, Santosh, Hu, Che-Ming Jack, Zhang, Liangfang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830398/
https://ncbi.nlm.nih.gov/pubmed/20039697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn9014032
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