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Active Site of α-Chymotrypsin Activation by Association-Desolvation

High reactivity toward α-chymotrypsin is observed for derivatives of β-arylpropionic acids of varied structure—L-α-acylamido compounds, D-cyclized compounds, and, now, L-glycolamide esters. Compensating enthalpy and entropy effects are observed which appear to be caused by changes in water of solvat...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cohen, Saul G., Vaidya, Vishnu M., Schultz, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283036/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16591836/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.66.2.249
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