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miRNA Mutations are Not a Common Cause of Deafness

Mutations in miRNA genes have been implicated in hearing loss in human families and mice. It is also possible that mutations in miRNA binding sites of inner ear targets alter gene expression levels and lead to hearing loss. To investigate these possibilities we screened predicted target genes of the...

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Hlavní autoři: Hildebrand, Michael S., Witmer, P. Dane, Xu, Shunbin, Newton, Stephen S., Kahrizi, Kimia, Najmabadi, Hossein, Valle, David, Smith, Richard J.H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830307/
https://ncbi.nlm.nih.gov/pubmed/20186779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.33299
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