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A consistent and efficient graphical analysis method to improve the quantification of reversible tracer binding in radioligand receptor dynamic PET studies

The widely used Logan plot in radioligand receptor dynamic PET studies produces marked noise-induced negative biases in the estimates of total distribution volume (DV(T)) and binding potential (BP). To avoid the inconsistencies in the estimates from the Logan plot, a new graphical analysis method wa...

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Detalhes bibliográficos
Main Authors: Zhou, Yun, Ye, Weiguo, Brašić, James R., Crabb, Andrew H., Hilton, John, Wong, Dean F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830275/
https://ncbi.nlm.nih.gov/pubmed/18930830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2008.09.021
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