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Targeting lentiviral vector to specific cell types through surface displayed single chain antibody and fusogenic molecule

BACKGROUND: Viral delivery remains one of the most commonly used techniques today in the field of gene therapy. However, one of the remaining hurdles is the off-targeting effect of viral delivery. To overcome this obstacle, we recently developed a method to incorporate an antibody and a fusogenic mo...

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Autori principali: Lei, Yuning, Joo, Kye-Il, Zarzar, Jonathan, Wong, Clement, Wang, Pin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830192/
https://ncbi.nlm.nih.gov/pubmed/20149250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-35
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