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Stimulated Formation of Adenosine 3′,5′-Cyclic Phosphate in Cerebral Cortex: Synergism between Electrical Activity and Biogenic Amines

When cortical slices are incubated with adenine-(14)C, adenine nucleotides are labeled in a small and relatively stable pool. The ATP-(14)C of this pool is readily converted to cAMP-(14)C during incubations with depolarizing agents, such as K(+), ouabain, veratridine, or batrachotoxin. During incuba...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Shimizu, Hirotoshi, Creveling, Cyrus R., Daly, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1970
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283019/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4314898/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.4.1033
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