Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice

Telomere shortening represents a causal factor of cellular senescence. At the same time, several lines of evidence indicate a pivotal role of oxidative DNA damage for the aging process in vivo. A causal connection between the two observations was suggested by experiments showing accelerated telomere...

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Main Authors: Guachalla, Luis Miguel, Ju, Zhenyu, Koziel, Rafal, von Figura, Guido, Song, Zhangfa, Fusser, Markus, Epe, Bernd, Jansen-Dűrr, Pidder, Rudolph, K. Lenhard
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830048/
https://ncbi.nlm.nih.gov/pubmed/20195488
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