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IL-21 Is Required to Control Chronic Viral Infection

CD4(+) and CD8(+) T cell functions are rapidly aborted during chronic infection, preventing viral clearance. CD4(+) T cell help is required throughout chronic infection so as to sustain CD8(+) T cell responses; however, the necessary factor(s) provided by CD4(+) T cells are currently unknown. Using...

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Detalhes bibliográficos
Main Authors: Elsaesser, Heidi, Sauer, Karsten, Brooks, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830017/
https://ncbi.nlm.nih.gov/pubmed/19423777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1174182
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