Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia

BACKGROUND: Cancer cachexia is a multi-organ tissue wasting syndrome that contributes to morbidity and mortality in many cancer patients. Skeletal muscle loss represents an established key feature yet there is no molecular understanding of the disease process. In fact, the postulated molecular regul...

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Bibliographic Details
Main Authors: Stephens, Nathan A, Gallagher, Iain J, Rooyackers, Olav, Skipworth, Richard J, Tan, Ben H, Marstrand, Troels, Ross, James A, Guttridge, Denis C, Lundell, Lars, Fearon, Kenneth C, Timmons, James A
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829926/
https://ncbi.nlm.nih.gov/pubmed/20193046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm122
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