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Biotin-Bound CO(2) and the Mechanism of Enzymatic Carboxylation Reactions

Considerations are provided which show that the carboxylation site (oxygen or nitrogen) of biotin is most likely unknown. Kinetic studies of intramolecular reactions of the ureido function at acyl carbon demonstrate that ureido oxygen attack is the preferred mode when the acyl group is activated. Tr...

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Библиографические подробности
Главные авторы: Bruice, Thomas C., Hegarty, A. F.
Формат: Artigo
Язык:Inglês
Опубликовано: 1970
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC282986/
https://ncbi.nlm.nih.gov/pubmed/5266151
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