Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome

Factor H autoantibodies have been reported in approximately 10% of patients with atypical hemolytic uremic syndrome (aHUS) and are associated with deficiency of factor H–related proteins 1 and 3. In this study we examined the prevalence of factor H autoantibodies in the Newcastle cohort of aHUS pati...

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Detalhes bibliográficos
Main Authors: Moore, Iain, Strain, Lisa, Pappworth, Isabel, Kavanagh, David, Barlow, Paul N., Herbert, Andrew P., Schmidt, Christoph Q., Staniforth, Scott J., Holmes, Lucy V., Ward, Roy, Morgan, Lynn, Goodship, Timothy H. J., Marchbank, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829859/
https://ncbi.nlm.nih.gov/pubmed/19861685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-221549
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