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Evaluating the Intrinsic Cysteine Redox-dependent States of the A-chain of H uman Insulin using NMR Spectroscopy, Quantum Chemical Calculations and Mass Spectrometry

Previous functional studies have proposed that solution-phase loading of human insulin A-chain peptides into cell surface Class II molecules may be limited by the redox state of intrinsic cysteine residues within the A-chain peptide. T cell functional studies of a human insulin A-chain analogue (KR...

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Hlavní autoři: Sharma, Alok K., Ling, Yan, Greer, Allison B., Hafler, David A., Kent, Sally C., Zhang, Yong, Rigby, Alan C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829747/
https://ncbi.nlm.nih.gov/pubmed/19954153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp908729h
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