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Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production

Calorie restriction (CR) slows aging and is thought to improve insulin sensitivity in laboratory animals. In contrast, decreased insulin signaling and/or mild insulin resistance paradoxically extends maximal lifespan in various genetic animal models of longevity. Nothing is known regarding the long-...

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Detalhes bibliográficos
Main Authors: Fontana, Luigi, Klein, Samuel, Holloszy, John O.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829643/
https://ncbi.nlm.nih.gov/pubmed/19904628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-009-9118-z
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