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Regulatory Activity Revealed by Dynamic Correlations in Gene Expression Noise

Gene regulatory interactions are context–dependent, active in some cellular states but not others. Stochastic fluctuations, or ‘noise,’ in gene expression propagate through active, but not inactive, regulatory links [1, 2]. Thus, correlations in gene expression noise could provide a non-invasive mea...

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Detalhes bibliográficos
Main Authors: Dunlop, Mary J., Cox, Robert Sidney, Levine, Joseph H., Murray, Richard M., Elowitz, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829635/
https://ncbi.nlm.nih.gov/pubmed/19029898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.281
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