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Synthesis and application of molecular probe for detection of hydroxyl radicals produced by Na(125)I and γ-rays in aqueous solution

PURPOSE: To synthesize N-(3-(3-aminopropylamino)propyl)-2-oxo-2H-chromene-3-carboxamide (7), a novel DNA-binding, coumarin-based, fluorescent hydroxylradical ((·)OH) indicator and to assess its quantum efficiency compared with that of coumarin-3-carboxylic acid (1) and N1,N12-bis[2-oxo-2H-chromene-3...

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Main Authors: SINGH, AMARJIT, YANG, YONGLIANG, ADELSTEIN, S. JAMES, KASSIS, AMIN I.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829608/
https://ncbi.nlm.nih.gov/pubmed/19061124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09553000802552143
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