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Mechanics of Frameshift Mutagenesis in Bacteriophage T4: Role of Chromosome Tips

In contrast to observations in bacteria and fungi, frameshift mutations in bacteriophage T4 do not arise during genetic recombination. Nascent mutants, captured in the heterozygous condition, exhibit properties which indicate that the new lesions are located at the extreme tips of the chromosomes, a...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lindstrom, Dona M., Drake, John W.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1970
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282951/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4910850/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.3.617
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