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Labeling and Other Effects of Actinomycin D on Human Chromosomes

(3)H-actinomycin D, a guanine-binding agent, labels fixed human chromosomes nonrandomly. Actinomycin D added in G2 inhibits secondary constrictions and breaks chromosomes. There is some tendency for label to be concentrated at the ends of chromosomes and near the centromere. Labeling with (3)H-thymi...

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Detalhes bibliográficos
Autor principal: Miles, Charles P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC282947/
https://ncbi.nlm.nih.gov/pubmed/5267140
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