Gene Expression in Lung and Liver After Intravenous Infusion of Polyethylenimine Complexes of Sleeping Beauty Transposons

Two methods of systemic gene delivery have been extensively explored, using the mouse as a model system: hydrodynamic delivery, wherein a DNA solution equivalent in volume to 10% of the mouse weight is injected intravenously in less than 10 sec, and condensation of DNA with polyethylenimine (PEI) fo...

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Autors principals: Podetz-Pedersen, Kelly M., Bell, Jason B., Steele, Terry W.J., Wilber, Andrew, Shier, W. Thomas, Belur, Lalitha R., McIvor, R. Scott, Hackett, Perry B.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829452/
https://ncbi.nlm.nih.gov/pubmed/19761403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.128
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