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Long-Term Luciferase Expression Monitored by Bioluminescence Imaging After Adeno-Associated Virus-Mediated Fetal Gene Delivery in Rhesus Monkeys (Macaca mulatta)

The safety and efficiency of fetal adeno-associated virus (AAV) gene delivery in rhesus monkeys and long-term monitoring of transgene expression by bioluminescence imaging (BLI) were evaluated. Early second-trimester fetal monkeys were administered AAV2/5, AAV2/9, or AAV2/10 vector supernatant prepa...

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Detalhes bibliográficos
Main Authors: Tarantal, Alice F., Lee, C. Chang I.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829449/
https://ncbi.nlm.nih.gov/pubmed/19751148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.126
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