A Genetic Variant BDNF Polymorphism Alters Extinction Learning in Both Mouse and Human

Mouse models are useful for studying genes involved in behavior, but whether they are relevant for human behavior is unclear. Here, we identified parallel phenotypes in mice and humans resulting from a common single-nucleotide polymorphism in the brain-derived neurotrophic factor (BDNF) gene, which...

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Detalhes bibliográficos
Main Authors: Soliman, Fatima, Glatt, Charles E., Bath, Kevin G., Levita, Liat, Jones, Rebecca M., Pattwell, Siobhan S., Jing, Deqiang, Tottenham, Nim, Amso, Dima, Somerville, Leah H., Voss, Henning U., Glover, Gary, Ballon, Douglas J., Liston, Conor, Teslovich, Theresa, Van Kempen, Tracey, Lee, Francis S., Casey, BJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829261/
https://ncbi.nlm.nih.gov/pubmed/20075215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1181886
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