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Conformational Changes of an Ion Channel Detected Through Water-Protein Interactions Using Solid-State NMR Spectroscopy

The influenza A virus M2 protein is a pH-gated and amantadine-inhibited proton channel important for the virus life cycle. Proton conduction by M2 is known to involve water, however direct experimental evidence of M2-water interaction is scarce. Using (1)H spin diffusion solid-state NMR, we have now...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Luo, Wenbin, Hong, Mei
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829254/
https://ncbi.nlm.nih.gov/pubmed/20112896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9096219
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