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Conformational Changes of an Ion Channel Detected Through Water-Protein Interactions Using Solid-State NMR Spectroscopy
The influenza A virus M2 protein is a pH-gated and amantadine-inhibited proton channel important for the virus life cycle. Proton conduction by M2 is known to involve water, however direct experimental evidence of M2-water interaction is scarce. Using (1)H spin diffusion solid-state NMR, we have now...
में बचाया:
मुख्य लेखकों: | , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2010
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829254/ https://ncbi.nlm.nih.gov/pubmed/20112896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9096219 |
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