HipHop interacts with HOAP and HP1 to protect Drosophila telomeres in a sequence-independent manner

Telomeres prevent chromosome ends from being repaired as double-strand breaks (DSBs). Telomere identity in Drosophila is determined epigenetically with no sequence either necessary or sufficient. To better understand this sequence-independent capping mechanism, we isolated proteins that interact wit...

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Bibliografske podrobnosti
Main Authors: Gao, Guanjun, Walser, Jean-Claude, Beaucher, Michelle L, Morciano, Patrizia, Wesolowska, Natalia, Chen, Jie, Rong, Yikang S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829166/
https://ncbi.nlm.nih.gov/pubmed/20057353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.394
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