A tyrosine PEG-micelle magnetic resonance contrast agent for the detection of lipid rich areas in atherosclerotic plaque

Vulnerable or high-risk atherosclerotic plaques often exhibit large lipid cores and thin fibrous caps that can lead to deadly vascular events via their rupture. In this study, PEG-micelles that incorporate a Gd-DTPA amphiphile were used as an MR contrast agent. In an approach inspired by lipoprotein...

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Main Authors: Beilvert, Anne, Cormode, David P., Chaubet, Frédéric, Briley-Saebo, Karen C., Mani, Venkatesh, Mulder, Willem J.M., Vucic, Esad, Toussaint, Jean-François, Letourneur, Didier, Fayad, Zahi A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829093/
https://ncbi.nlm.nih.gov/pubmed/19780153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22103
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