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Broadly Protective Monoclonal Antibodies against H3 Influenza Viruses following Sequential Immunization with Different Hemagglutinins

As targets of adaptive immunity, influenza viruses are characterized by the fluidity with which they respond to the selective pressure applied by neutralizing antibodies. This mutability of structural determinants of protective immunity is the obstacle in developing universal influenza vaccines. Tow...

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Detalhes bibliográficos
Main Authors: Wang, Taia T., Tan, Gene S., Hai, Rong, Pica, Natalie, Petersen, Erin, Moran, Thomas M., Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829068/
https://ncbi.nlm.nih.gov/pubmed/20195520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000796
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