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On-chip activation and subsequent detection of individual antigen-specific T cells
The frequencies of antigen-specific CD4+ T cells in samples of human tissue has been difficult to determine accurately ex vivo, particularly for autoimmune diseases such as multiple sclerosis or Type 1 diabetes. Conventional approaches involve the expansion of primary T cells in vitro to increase th...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828941/ https://ncbi.nlm.nih.gov/pubmed/20000848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac9024363 |
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