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Systematic mapping of the state dependence of voltage- and Ca(2+)-dependent inactivation using simple open-channel measurements

The state from which channel inactivation occurs is both biologically and mechanistically critical. For example, preferential closed-state inactivation is potentiated in certain Ca(2+) channel splice variants, yielding an enhancement of inactivation during action potential trains, which has importan...

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Autori principali: Tadross, Michael R., Yue, David T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828911/
https://ncbi.nlm.nih.gov/pubmed/20142518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910309
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