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Genome rearrangements activate the Epstein-Barr virus gene whose product disrupts latency.
A defective Epstein-Barr virus (EBV) containing a deleted and rearranged genome (het DNA) causes latent EBV to replicate. This activity maps to the 2.7-kilobase-pair WZhet fragment. The BZLF1 open reading frame, present within WZhet as well as in the standard viral BamHI Z fragment, encodes the prot...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2849118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9801 |
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