Genome rearrangements activate the Epstein-Barr virus gene whose product disrupts latency.

A defective Epstein-Barr virus (EBV) containing a deleted and rearranged genome (het DNA) causes latent EBV to replicate. This activity maps to the 2.7-kilobase-pair WZhet fragment. The BZLF1 open reading frame, present within WZhet as well as in the standard viral BamHI Z fragment, encodes the prot...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Rooney, C, Taylor, N, Countryman, J, Jenson, H, Kolman, J, Miller, G
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1988
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2849118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9801
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