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Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

Endothelin releases prostacyclin and thromboxane A2 from guinea pig or rat isolated lungs and endothelium-derived relaxing factor in the perfused mesentery of the rat. Endothelin is also substantially removed by the pulmonary circulation of the rat in vitro and in vivo and by guinea pig lungs in vit...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: de Nucci, G, Thomas, R, D'Orleans-Juste, P, Antunes, E, Walder, C, Warner, T D, Vane, J R
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1988
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282868/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3059352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9797
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