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Kinetochores Generate Microtubules with Distal Plus Ends: Their Roles and Limited Lifetime in Mitosis

In early mitosis, microtubules can be generated at kinetochores as well as at spindle poles. However, the role and regulation of kinetochore-derived microtubules have been unclear. In general, metaphase spindle microtubules are oriented such that their plus ends bind to kinetochores. However, we now...

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Detalhes bibliográficos
Main Authors: Kitamura, Etsushi, Tanaka, Kozo, Komoto, Shinya, Kitamura, Yoko, Antony, Claude, Tanaka, Tomoyuki U.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828607/
https://ncbi.nlm.nih.gov/pubmed/20159595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.12.018
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