Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells.

The nonobese diabetic (NOD) mouse has been developed as a model for insulin-dependent diabetes. One gene required for the development of diabetes is associated with the major histocompatibility complex. This gene possibly could be linked to class II genes, which show a unique pattern in NOD mice. To...

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Main Authors: Boitard, C, Bendelac, A, Richard, M F, Carnaud, C, Bach, J F
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC282848/
https://ncbi.nlm.nih.gov/pubmed/3264405
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