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Rapid separation and purification of oligonucleotides by high-performance capillary gel electrophoresis.

Picomole amounts of oligodeoxynucleotides [polydeoxyadenylic acids, (dA)40-60] were baseline resolved and analyzed in less than 8 min by high-performance capillary electrophoresis with polyacrylamide gels. In addition, fast analysis of a crude 70-mer oligodeoxynucleotide and a slab gel-purified 99-m...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Cohen, A S, Najarian, D R, Paulus, A, Guttman, A, Smith, J A, Karger, B L
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3200850/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9660
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