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TGFβ Inducible Early Gene-1 Directly Binds to, and Represses, the OPG Promoter in Osteoblasts

TGFβ Inducible Early Gene-1 (TIEG) is a member of the Krüppel-like family of transcription factors (KLF10) that plays an important role in TGFβ mediated Smad signaling. In order to better understand the role of TIEG in bone, we generated TIEG knockout (KO) mice. Calvarial osteoblasts (OBs) isolated...

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Dettagli Bibliografici
Autori principali: Subramaniam, M., Hawse, J. R., Bruinsma, E. S., Grygo, S. B., Cicek, M., Oursler, M. J., Spelsberg, T. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828289/
https://ncbi.nlm.nih.gov/pubmed/20059964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.12.171
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