Intrapartum Tenofovir and Emtricitabine Reduces Low-Concentration Drug Resistance Selected by Single-Dose Nevirapine for Perinatal HIV Prevention

A single dose of tenofovir/emtricitabine (TDF/FTC) during labor significantly reduces peripartum nevirapine-associated viral drug resistance when measured by consensus HIV sequencing. It is unknown whether this effect extends to HIV subpopulations of <25–50%. We conducted a randomized trial of si...

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Detalhes bibliográficos
Main Authors: Chi, Benjamin H., Ellis, Giovanina M., Chintu, Namwinga, Cantrell, Ronald A., Sinkala, Moses, Aldrovandi, Grace M., Warrier, Ranjit, Mbewe, Felistas, Nakamura, Kyle, Stringer, Elizabeth M., Frenkel, Lisa M., Stringer, Jeffrey S.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Clinical Trials/Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828257/
https://ncbi.nlm.nih.gov/pubmed/19886836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2009.0088
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