Mode of Coreceptor Use by R5 HIV Type 1 Correlates with Disease Stage: A Study of Paired Plasma and Cerebrospinal Fluid Isolates

Through the use of chimeric CXCR4/CCR5 receptors we have previously shown that CCR5-tropic (R5) HIV-1 isolates acquire a more flexible receptor use over time, and that this links to a reduced viral susceptibility to inhibition by the CCR5 ligand RANTES. These findings may have relevance with regards...

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Dettagli Bibliografici
Autori principali: Karlsson, Ulf, Antonsson, Liselotte, Repits, Johanna, Medstrand, Patrik, Owman, Christer, Kidd-Ljunggren, Karin, Hagberg, Lars, Svennerholm, Bo, Jansson, Marianne, Gisslén, Magnus, Ljungberg, Bengt
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2009
Soggetti:
Virology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828237/
https://ncbi.nlm.nih.gov/pubmed/20001314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2009.0069
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