The ecto-nucleotidase NTPDase1 differentially regulates P2Y1 and P2Y2 receptor-dependent vasorelaxation

BACKGROUND AND PURPOSE: Extracellular nucleotides produce vasodilatation through endothelial P2 receptor activation. As these autacoids are actively metabolized by the ecto-nucleotidase nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), we studied the effects of this cell surface enzyme on nuc...

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Detalhes bibliográficos
Main Authors: Kauffenstein, Gilles, Fürstenau, Cristina Ribas, D'Orléans-Juste, Pedro, Sévigny, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828022/
https://ncbi.nlm.nih.gov/pubmed/20067476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00566.x
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