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Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice

Despite the high doses of radiation delivered in the treatment of patients with glioblastoma multiforme (GBM), the tumors invariably recur within the irradiation field, resulting in a low cure rate. Understanding the mechanism of such recurrence is therefore important. Here we have shown in an intra...

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Detalhes bibliográficos
Main Authors: Kioi, Mitomu, Vogel, Hannes, Schultz, Geoffrey, Hoffman, Robert M., Harsh, Griffith R., Brown, J. Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827954/
https://ncbi.nlm.nih.gov/pubmed/20179352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40283
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