In Vivo Detection of Extrapancreatic Insulin Gene Expression in Diabetic Mice by Bioluminescence Imaging

BACKGROUND: Extrapancreatic tissues such as liver may serve as potential sources of tissue for generating insulin-producing cells. The dynamics of insulin gene promoter activity in extrapancreatic tissues may be monitored in vivo by bioluminescence-imaging (BLI) of transgenic mice Tg(RIP-luc) expres...

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Bibliographic Details
Main Authors: Chen, Xiaojuan, Larson, Courtney S., West, Jason, Zhang, Xiaomin, Kaufman, Dixon B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827564/
https://ncbi.nlm.nih.gov/pubmed/20195523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009397
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