Axin downregulates TCF-4 transcription via β-catenin, but not p53, and inhibits the proliferation and invasion of lung cancer cells

BACKGROUND: We previously reported that overexpression of Axin downregulates T cell factor-4 (TCF-4) transcription. However, the mechanism(s) by which Axin downregulates the transcription and expression of TCF-4 is not clear. It has been reported that β-catenin promotes and p53 inhibits TCF-4 transc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yang, Lian-He, Xu, Hong-Tao, Han, Yang, Li, Qing-Chang, Liu, Yang, Zhao, Yue, Yang, Zhi-Qiang, Dong, Qian-Ze, Miao, Yuan, Dai, Shun-Dong, Wang, En-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827467/
https://ncbi.nlm.nih.gov/pubmed/20122174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-25
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados