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Incorporating demographic stochasticity into multi-strain epidemic models: application to influenza A

We develop mathematical models of the transmission and evolution of multi-strain pathogens that incorporate strain extinction and the stochastic generation of new strains via mutation. The dynamics resulting from these models is then examined with the applied aim of understanding the mechanisms unde...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Minayev, Pavlo, Ferguson, Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827439/
https://ncbi.nlm.nih.gov/pubmed/19158010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2008.0467
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