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Comparative analysis of missing value imputation methods to improve clustering and interpretation of microarray experiments

BACKGROUND: Microarray technologies produced large amount of data. In a previous study, we have shown the interest of k-Nearest Neighbour approach for restoring the missing gene expression values, and its positive impact of the gene clustering by hierarchical algorithm. Since, numerous replacement m...

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Autors principals: Celton, Magalie, Malpertuy, Alain, Lelandais, Gaëlle, de Brevern, Alexandre G
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827407/
https://ncbi.nlm.nih.gov/pubmed/20056002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-15
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