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Reversion toward an earlier stage of differentiation and loss of polarity during progression of N-methyl-N-nitrosourea-induced rat mammary tumours.

To work toward an understanding of the mechanisms of cancer progression, we have followed the changes in expression of several genes in rat mammary carcinomas during the development of invasion. Tumors were induced by N-methyl-N-nitrosourea and serially transplanted to isogeneic rats. Gene expressio...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Dulbecco, R, Armstrong, B, Allen, R
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2461567/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9292
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