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Missense mutations in an infectious human immunodeficiency viral genome: functional mapping of tat and identification of the rev splice acceptor.

Single nucleotide alterations were introduced into an infectious clone of human immunodeficiency virus type 1 to create a series of missense mutants in the tat coding region. Although mutations in a proline-rich region and a basic lysine-arginine-rich region resulted in wild-type phenotypes, five of...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sadaie, M R, Rappaport, J, Benter, T, Josephs, S F, Willis, R, Wong-Staal, F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3194421/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9224
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