Effect of mutations and variations of HLA-A2 on recognition of a virus peptide epitope by cytotoxic T lymphocytes.

Cytotoxic T lymphocytes (CTL) specific for influenza A virus were prepared from 15 donors. Those with HLA-A2 recognized autologous or HLA-A2-matched B-lymphoblastoid cells in the presence of synthetic peptide representing residues 55-73 or 56-68 of the virus matrix protein sequence. Influenza A viru...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	McMichael, A J, Gotch, F M, Santos-Aguado, J, Strominger, J L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282705/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2461564/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9194
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