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HSV Type 2 Infection Increases HIV DNA Detection in Vaginal Tissue of Mice Expressing Human CD4 and CCR5

The goal of this study was to develop an in vivo murine model that can be used to study the influence of HSV-2 on HIV infection. Mice expressing transgenes for human CD4, CCR5, and Cyclin T1 were infected intravaginally with HSV-2 and 3–7 days later infected with HIV. HIV DNA was detected by real-ti...

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Detalhes bibliográficos
Main Authors: Zariffard, M. Reza, Saifuddin, Mohammed, Finnegan, Alison, Spear, Gregory T.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826840/
https://ncbi.nlm.nih.gov/pubmed/19886831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2009.0035
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