Case Report: Successful Sporozoite Challenge Model in Human Volunteers with Plasmodium vivax Strain Derived from Human Donors

Successful establishment of a Plasmodium vivax sporozoite challenge model in humans is described. Eighteen healthy adult, malaria-naïve volunteers were randomly allocated to Groups A–C and exposed to 3 ± 1, 6 ± 1, and 9 ± 1 bites of Anopheles albimanus mosquitoes infected with P. vivax, respectively...

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Main Authors: Herrera, Sócrates, Fernández, Olga, Manzano, María R., Murrain, Bermans, Vergara, Juana, Blanco, Pedro, Palacios, Ricardo, Vélez, Juan D., Epstein, Judith E., Chen-Mok, Mario, Reed, Zarifah H., Arévalo-Herrera, Myriam
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826834/
https://ncbi.nlm.nih.gov/pubmed/19861603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2009.09-0194
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