Physiological numbers of CD4(+) T cells generate weak recall responses following influenza virus challenge

Naïve and recall CD4(+) T cell responses were probed with recombinant influenza A viruses incorporating the ovalbumin (OVA) OT-II peptide. The extent of OT-II specific CD4(+) T cell expansion was greater following primary exposure, with secondary challenge achieving no significant increase in number...

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Bibliografiske detaljer
Main Authors:	Thomas, Paul G., Brown, Scott A., Morris, Melissa Y., Yue, Wen, So, Jenny, Reynolds, Cory, Webby, Richard J., Doherty, Peter C.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2010
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2826830/ https://ncbi.nlm.nih.gov/pubmed/20061406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901427
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Physiological numbers of CD4(+) T cells generate weak recall responses following influenza virus challenge

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