Rabies virus-based vaccines elicit neutralizing antibodies, poly-functional CD8(+) T cell, and protect rhesus macaques from AIDS-like disease after SIV(mac251) challenge

Highly attenuated rabies virus (RV) vaccine vectors were evaluated for their ability to protect against highly pathogenic SIV(mac251) challenge. Mamu-A*01 negative rhesus macaques were immunized in groups of four with either: RV expressing SIV(mac239)-GagPol, a combination of RV expressing SIV(mac23...

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Detalhes bibliográficos
Main Authors: Faul, Elizabeth J., Aye, Pyone P., Papaneri, Amy B., Pahar, Bapi, McGettigan, James P., Schiro, Faith, Chervoneva, Inna, Montefiori, David C., Lackner, Andrew A., Schnell, Matthias J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826816/
https://ncbi.nlm.nih.gov/pubmed/19879223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.10.051
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