Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-R(KT), a major regulator of cell surface plasminogen activation

Activation of plasminogen, the zymogen of the primary thrombolytic enzyme, plasmin, is markedly promoted when plasminogen is bound to cell surfaces, arming cells with the broad spectrum proteolytic activity of plasmin. In addition to its role in thrombolysis, cell surface plasmin facilitates a wide...

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Main Authors: Andronicos, Nicholas M., Chen, Emily I., Baik, Nagyung, Bai, Hongdong, Parmer, Caitlin M., Kiosses, William B., Kamps, Mark P., Yates, John R., Parmer, Robert J., Miles, Lindsey A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2010
Assuntos:
Plenary Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826757/
https://ncbi.nlm.nih.gov/pubmed/19897580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-188938
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