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Schwann Cells Inhibit Ectopic Clustering of Axonal Sodium Channels

The clustering of voltage-gated sodium channels at the axon initial segment (AIS) and nodes of Ranvier is essential for the initiation and propagation of action potentials in myelinated axons. Sodium channels localize to the AIS through an axon-intrinsic mechanism driven by ankyrin G, while clusteri...

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Autori principali: Voas, Matthew G., Glenn, Thomas D., Raphael, Alya R., Talbot, William S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826614/
https://ncbi.nlm.nih.gov/pubmed/19923275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0841-09.2009
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